Monday, October 14, 2024

Your Workout Today May Trigger A bright Idea Next Week

Picture from Triana et al (2024)
What if I told you your exercise session today can trigger a bright idea next week? That's exactly what a recent study by Finnish researchers found. They tracked a person's brain and behavioural activity for 5 months using brain scans and data from smart phones and wearable devices

This research (Trinan et al, 2024) was unusual since few brain scan studies involve such detailed monitoring over months. Using wearable technology in this study was crucial, especially since brain scans (while being useful) only shows the subject lying still for 30 minutes. 

2 distinct patterns were identified by the researchers. A short term wave that lasted under 7 days and a long term wave by up to 15 days. The short term wave reflects rapid adaptations like how focus is affected by poor sleep although it recovers quickly. The long term wave suggests more gradual, lasting effects, especially in areas tied to our attention and memory.

The study found that our brains do not respond to our activities of daily living in immediate, isolated bursts. Our brain activity evolves in response to our sleep patterns, physical activity, mood, and respiration rate over many days. This means that your exercise session or a restless night from the previous week can still affect your brain. Hence your memory, cognition and attention can be affected well into the next week.

It is a great study linking brain activity with environmental and physiological data as tracking our brain changes in real time can help detect mental health and neurological disorders early. This allows for earlier interventions and better outcomes.

Even though this study was not focused exclusively on exercise, the results showed that we definitely need a consistent exercise routine and maintain good sleep habits for our overall well being. I find myself particularly sensitive to these as I age. 

Reference

Triana AM, Salmi J, Hayward NME et al (2024). Longitudinal Single-subject Neuroimaging Study Reveals Effects Of Daily Environmental, Physiological, And Lifestyle Factors On Functional Brain Connectivity. Plos Bio. DOI: 10.1371/journal.pbio.3002797

Sunday, October 6, 2024

Something You Do Not Know About Muscles

Picture from Burke et al, 2024
This is a very interesting finding about muscles. The muscles we use while exercising can actually communicate with our adipose (fat) stores in our body.

This study was done with 32 human subjects. A single bout of resistance exercise (or strength training) releases muscle specific microRNA-1 (miR-1) from muscles that are then transported to abdominal fat tissue via extracellular vesicles or EVs to stimulate lipolysis. Lipolysis is the breakdown of fats and other lipids to release fatty acids. This means you can use fats for energy, sparing your carbohydrate and protein.

I know what some of you reading must be thinking. Is spot reduction possible? Spot reduction means selective loss of body fat in regions involved in the exercise. Meaning can we isolate the fat in the abdomen (for men) by doing cruches or sit-ups?  Or doing lunges for the buttock and thighs (for women) and get rid of the fat there first? 

Well, sorry to disappoint you. In this study, the exercises were mainly done in the lower body- squats, leg press, leg extension and also lat pulldown (for the upper body). 3 sets of 8 reps at 80 percent of 1 rep max on the aboved mentioned exercises were performed. A fourth set to failure was performed straight after.

The lipolysis or fat breakdown in the adipose tissue was in a non specific area - the abdominal region. This was confirmed by the EV's found there.

Perhaps this is an interesting consideration suggesting that our muscles can function like a secretory organ. Like a giant endocrine organ in the body, more than we realize anyway. (Note : thoughts are my own, not from the study).

We are definitely only scratching the surface of understanding how exercise has so many other unknown benefits.

The women in the study did not have as strong an effect compared to the men in the study. Also note that is is a relatively small study with only 32 subjects.

If you are not already doing any strength training, you should. Not only it can increase your bone density, helps with insulin sensitivity, promote better sleep etc, it can also break down your stored fat.

Reference

Burke BI, Ismaeel A, Long DE et al (2024). Extracellular Vesicle Transfer Of miR-1 To Adipose Tissue Modifys Lipolythic Pathways Following Resistance Exercise. JCI Insight. DOI: 10.1172/jci.insight.182589